We are all aware of the fact that slimming is a mega-dollar industry. With millions, if not billions of people of every age group struggling to shed weight, and extremely few pharmaceutically effective medications available to assist them, the desperate public will literally clutch at straws.
Each week sees the launch of the new “miracle” diet pill or potion as well as a “surefire” diet bound to help believers shed kilos like magic.
Recently dr oz on garcinia took over as the flavour of year. In the event you search the net for info on this exotic fruit extract you will end up assured that this is finally the miracle most of us have been waiting for, that can produce dramatic weight loss. Endorsements by various TV personalities and also other luminaries have added to the allure of Garcinia cambogia slimming products.
According to a newly released local study in the Tshwane University of Technology (TUT) “this small fruit, reminiscent of a pumpkin in looks, is currently most popularly used and widely advertised as a weight-loss supplement”.
The comprehensive overview from TUT demonstrates that studies have shown that “the extracts along with (-)-hydroxycitric acid (HCA), a main organic acid element of the fruit rind, exhibited anti-obesity activity”. Furthermore, it regulates the serotonin levels linked to satiety, ultimately causing reduced food intake.
“According to clinical trial reports, Garcinia extracts were good for obese individuals on many occasions. In addition, studies on the toxicity and observations during clinical studies indicate that Garcinia is safe for use. The majority of the negative reports happen to be relevant to instances when multi ingredient formulations were consumed and the effect could stop being related to a particular ingredient.”
The research does, however, caution against an increase in serotonin, especially in people who take medicines that are already increasing serotonin levels, such as SSRIs. Research into these effects has not been conducted.
“Moreover, regulatory authorities should provide and enforce legislation requiring the compulsory basic safety illustration showing supplements pre-marketing and develop post-marketing surveillance systems,” the analysis concluded.
Dr Ingrid van Heerden, an authorized dietitian, is of opinion that people must be cautious of how does garcinia work, because it has not yet undergone rigorous testing. What follows is reviewed information from her pen, including her final verdict:
Often, once a person who wants, or needs to lose excess weight, is totally hooked on the promise of a slim, sexy figure, they can be sucked in to the deception. In case the drops, wafers or powders don’t work, well then it is the fault of your user who failed to comply with one or other often impossible instruction including “stick to a 500 kcal/day diet” or “drink 5 litres water a day”, never that from the diet program pill.
When eventually science and legislation meet up with the makers, they calmly take product A away from the market, change their formulation slightly, affect the name to product B, and after that blithely sell product B utilizing the same advertising gambits as before, raking in the money and pulling the wool over everyone’s eyes over again.
In keeping with the ever-changing slimming product ranges, there are actually what one can call “ingredients of the year” (sometimes an ingredient lasts for only 3 to 6 months, however some have longer life spans, and then needless to say some are resurrected every 2-3 years).
We have had apple cider vinegar (which contains made many a comeback through the years), green tea extract (which contains earned some merit in scientific studies), hoodia (which just does not manage to make the research results that will make it a front-runner), willow bark (or salicylic acid which is useful for pains and aches yet not as efficacious for slimming), and good old caffeine (that has a diuretic effect thus helping you to lose weight till you replenish this type of water within your body, as well as a stimulant effect when taken in big amounts that can be potentially dangerous), to mention but a few.
Even though it is perfectly likely that more extensive and well controlled scientific research will disclose that this extract of Garcinia cambogia containing a chemical called hydroxycitric acid (HCA) can assist weight-loss, we are at present not sure how this tamarind or brindall berry or brindleberry or Garcinia gummi-gutta works, what side-effects it may or may not have and what dosage is required to achieve really significant weight-loss.
But I hear you say: “For once there exists a number of research studies which were performed with Garcinia cambogia, so what’s the problem?”
Well some of the studies failed to show any weight loss differences between patients who took Garcinia pills and those that took dummy pills, while other studies did show variations in weight reduction together with the subjects taking pills containing Garcinia losing slightly more weight than others that failed to (Marquez et al, 2012).
Many of these weight loss differences were not exactly exciting either, so we can’t say for sure that Garcinia cambogia does promote weight loss. Furthermore, it seems likely that this may not be the wonder pill it really is made over to be.
In addition, lots of the studies conducted to date happen to be flawed (Critchley, 2013) . What it means is made for example that in a study the control and experimental subjects were not well matched (i.e. they did not have the same starting weight, age, percentage of unwanted fat etc.), whilst in other studies too few subjects were utilised for that results to be significant.
For that results of studies to be plausible one must compare “apples with apples” (i.e. well-matched subjects and controls) and you need not just a handful of subjects to produce exactly the same result.
Around the positive side, we are able to state that there is some evidence that Garcinia cambogia products may aid weight loss over a duration of 12 weeks. No studies have been conducted for longer periods as yet (Marquez et al, 2012), which is viewed as a drawback.
Additionally there is currently an argument regarding the safety of pills containing Garcinia cambogia – one band of researchers slates the pills as dangerous and hepatotoxic (causing liver damage) (Kim et al, 2013), while another group refutes this (Clouatre & Preuss, 2013). Marquez and his awesome coworkers (2012) declare that “at the doses usually administered, no differences have already been reported regarding unwanted effects or adverse events (those studied) in humans between individuals treated with G. cambogia and controls.”
Ano Lob (2009), a public health consultant in the United States has published a warning regarding the hepatotoxicity of a weight loss product called “Hydroxycut”, containing Garcinia cambogia. The author collected case reports of patients who developed liver toxicity associated with the above mentioned weight reduction product.
Evidently approximately a million units of the hydroxycitric acid product are offered a year in the united states. The patients who developed hepatotoxicity reported signs of fatigue, nausea, vomiting, cramps, fever, chills, abdominal pain, and jaundice.
While the volume of hepatotoxicity cases reported were hardly any, Lob indicates that monitoring of adverse events related to nutritional supplements like these fat loss products is woefully inadequate in the united states (as is the case in numerous other countries, including South Africa), together with the FDA only receiving about 1% of those negative reports.
As outlined by Lob (2009), the Poison Control Centres in the united states will probably receive reports of adverse events linked to health supplements but are not equipped to coordinate such findings.
He cites the truly sobering example of something called “Metabolife 356″ that has been sold as a weight loss supplement in the us. Lob’s states how the manufacturers received 14 000 reports over a duration of 5 years that documented “serious adverse events related to their ephedra-containing product” which dexrpky17 heart attacks, strokes, convulsions and fatalities.
The manufacturers did not inform the FDA or any other US government authority of the reports. As astounding simply because this may sound, manufacturers of nutritional supplements are not expected to meet any of the specifications which can be strictly enforced when it comes to food and pharmaceutical products (medicines), to enable them to make use of this “ethical loophole” never to publish reports of negative and harmful events.
Eventually these events got to light and ephedra-containing products for slimming and other uses were banned in the united states.
The implication contain in Lob’s warning is the fact that HCA or Garcinia cambogia extract will also be potentially toxic unless sufficient, reliable evidence towards the contrary is produced available.
On the present moment, we do not know enough about slimming goods that contain the side effects of garcinia cambogia to freely recommend its use. I have a tendency to accept Astell and coworkers (2013) who conducted a systematic overview of double blind randomised controlled numerous studies to gauge evidence available on the efficacy of current vitamin supplements accustomed to control appetite and/or weight.
These authors figured that “According on the finding using this systematic review, evidence is just not convincing in demonstrating that a lot of health supplements used as appetite suppressants for weight-loss in the management of obesity are effective and safe.”
While we await more extensive and conclusive evidence obtained with larger numbers of well-matched test subjects treated for much longer periods using the “gold standard” of double blind randomised controlled clinical trials, rather avoid using any weight-loss supplement that is not tested thoroughly.